Biological implants play a crucial role in routine clinical practices. These implants help in replacement or stabilization of injured tissue either permanently or transiently. Repairing non-unions, fixing fractures, lens prosthesis, total joint replacements, ocular implants, soft tissue repair, cochlear implants, and spinal reconstruction are some of the major applications of the biological implants. The major challenge faced with the use of biological implants id their ability to stimulate tissue regeneration which now a days is of greater scientific interest and constitutes a key expanding field. Another challenge for the biologic implants, rapidly entering the marketplace is to undergo FDA regulations and reporting of adverse events.
Accidents on road and violence are a major cause of trauma which includes serious bone damage and internal bleeding. According to W.H.O. 3,400 deaths occur worldwide due to road accidents, and millions are injured who require medical attention. India ranks highest in the road accidents due to over populated roads and poor roads, and lack of traffic security. Accidents caused injuries lead to loss of appendage and serious fractures of extremities, cranial and spinal fractures. There is also a rise in two wheeler users in India who are more vulnerable to accidents. Sports like bike and car races, football, ice skiing, ice hockey, basketball, baseball, rugby, football, horse racing, and others which involve intense physical activities are also a major cause of joint replacement and trauma. The figures are more concerning in the lower age group. Around 3 million children under the age group of 14 are injured annually in sports activities.
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The global biological implants market can be segmented based on origin, applications, and geography. Applications segment comprises cardiovascular, orthopedics, neurological, nephrological, dental, ophthalmic, urogenital and others. Origin of biological implants consists of allograft or xenograft. Geographically, North America is expected to be the largest regional market for biological implants due to an increase in orthopedic procedures, rise in incidence of obesity, rising incidences of road accidents and introduction of technologically advanced products. North America is a potential market for advanced products manufactured through innovation and transforming biomaterials technology. The region is anticipated to be followed by Europe owing to the rising demand for biological implants, especially in the orthopedic and cardiovascular applications.
According to the Centers for Disease Control and Prevention (CDC), high school athletes alone account for 2 million injuries, 50,000 doctor visits and 30,000 hospitalizations each year in the U.S. alone. Rise in youth sports injuries is fueled by an increase in overuse of the joints and repeated small trauma injuries. In addition, baby booming population in the U.S. is able to exercise under medical supervision; and may have to undergo surgeries such as hip and knee replacements, surgery for cartilage damage and others. The most common injuries include ankle sprain, plantar fasciitis, shoulder sprains and strains, rotator cuff tears and knee injuries. Thus, growing awareness about sports and exercises has led to rise in injuries and consequently a greater demand for biological implants.
Emerging economies in Asia Pacific and Latin America hold immense potential for the biological implants owing to their increasing population coupled with the presence of high unmet medical needs and rise in healthcare related customer expectations brought about by improvement in economic conditions. Rising per capita and disposable incomes have boosted the growth of the market in these regions. Additionally, the uncertain economic situation of the U.S. and Europe has compelled manufacturers to explore these potential emerging markets through acquisitions and collaborations.
Alphatec Spine, Inc., Allergan, Biomet, Inc, C.R. Bard, Globus Medical, Integra Lifescience Corporation, NuVasive, Regeneration Technologies, Inc., and Stryker Corporation are some of the key players in the global biological implants market.
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