The global market for mass spectroscopy is driven by advancing technology, however, it is also trimming life cycle of existing products. With technological advances, application of mass spectroscopy is increasing rapidly. This has expanded customer base for mass spectroscopy market. Current customers of mass spectroscopy in healthcare include diagnostic and forensic laboratories, research institutions, and pharmaceutical companies. Growing concerns for food and drug safety and increasing incidences of related complications has demanded better analytical methods. Increasing research costs and need for reliable analysis also has fueled mass spectroscopy market. In the recent past, there has been a surge in research and development activities in molecular biology, drug development, proteomics, biomarkers and gene expression studies. To address these needs, mass spectroscopy device manufacturers, are constantly engaged in developing the mass spectroscopy technology. Currently, North America and Europe account for more than 50% of the market owing to large number of academic and research institutes. However, growth prospects are higher in Asia Pacific region where developing economic conditions and increasing research expenses have boosted market growth. High price of devices has however restricted the market penetration in middle income countries.
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Spectrometry is a widely used technique in analytical chemistry to identify the contents in a test sample with the help of interaction between mass and energy. There are three major types of spectrometry techniques, which are divided based on the method of analyzing the test sample: atomic spectrometry, mass spectrometry and molecular spectrometry. Mass spectrometry is one of the most widely technique to analyze chemical contents in a sample based on mass-to-charge ratio of the ions. Mass spectrometry includes various technologies which include gas and liquid chromatography combined with mass spectrometry, matrix-assisted laser desorption/ionization (MALDI), time-of-flight mass spectrometry (TOFMS), quadrupole mass spectroscopy. In healthcare, mass spectroscopy is used to trace distribution of numerous biomolecules directly from tissue samples. The technique helps in analysis of peptides, proteins, pharmaceutical drugs and metabolites. Mass spectroscopy allows testing for multiple diseases using small amount of sample and also allows screening programs to be customize according to specific population which focuses on diseases most likely to be present in that population. Wide scope of applications has expanded mass spectroscopy market in healthcare sector.
Gas chromatography-mass spectrometry (GC-MS) combination systems provide quantitative analysis of the components along with mass spectrum. GC-MS systems find applications in pharmaceutical and chemical analysis, food and product safety, clinical and toxicology testing, and forensic and environmental studies. MALDI-TOF mass spectrometer uses a focused laser beam in the ultraviolet or infrared range to analyze solid samples in two stages: desorption of surface particles by laser beam and ionization of matrix (solvent). The technique is useful in clinical diagnostics, environmental and taxonomical research, food processing and quality control. Triple-quadrupole liquid chromatography-mass spectrometry is used in pharmaceutical research for pharmacokinetic screening, metabolite identification, impurity profiling and other related applications.
The technique is also used in analyzing samples for identifying drug and pesticide residues, identification and quantification of disease agents and carcinogens in food samples. In environmental sciences, it is used for identification of contaminants in water and soil. Inductively coupled plasma mass spectrometry (ICP-MS), a type of mass spectrometry technique, enables the detection of metal components in extremely low concentration and is majorly used for clinical and forensic applications where traces of metals are detected in samples such as urine, plasma and tissue fluids.
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